Evidence-Based Decisions In DVT Management Research Paper

Evidence-Based Decisions In DVT Management Research Paper

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Attached is rubric and PICOT template page to help develop and format paper how professor wants. Also attached is the two papers wrote to refer to type PICOT based of those two papers.
Example paper attached as to how the paper should look per professor. A total of 4 uploaded files to refer to Evidence-Based Decisions In DVT Management Research Paper


Using a PICO(T) Framework and Evidence to Develop Care Practices

Deep Vein Thrombosis (DVT) is a medical condition characterized by formation of blood clots in the deep veins. The condition is mostly seen in the lower extremities. In the first two assessments, we focused on DVT and how to locate credible research sources from diverse databases on the topic. Building on this foundation, this present evaluation employs a PICO(T) process to formulate a research question, identify sources of evidence, and evaluate findings that would inform evidence-based practice in the management of Deep Vein Thrombosis.

Use of the PICOT Approach in the Management of DVT in Patients

The PICO(T) approach can be used in the provision of care for patients with DVT. The approach is useful as it provides a systematic and evidence-based framework that healthcare professionals can use to effectively manage the condition in patients. For this project, the formulated PICO(T) question involves examining the effect if anticoagulant therapy on the risk of recurrent thrombosis and overall patient outcomes. The question serves as a guiding beacon for decision-making. The approach helps to ensure that any clinical decisions made are founded on the best available evidence. In this regard, the quality of care is enhanced and patient outcomes optimized. The research question can be formulated as follows: In adults diagnosed with DVT, does the administration of anticoagulant therapy compared to no anticoagulant therapy lower the risk of recurrent thrombosis and improve patient outcomes within a timeframe of six months? Evidence-Based Decisions In DVT Management Research Paper

Based on the above question, the population is adult patients diagnosed with DVT. The proposed intervention is administration of anticoagulant therapy. Further, the intervention is compared to no anticoagulant therapy in the given population. The outcome subjected to the evaluation is the risk of recurrent thrombosis and improvement of patient outcomes. The timeframe is six months. According to Salvi et al. (2020), the proposed intervention of anticoagulant therapy administration in the given population plays a pivotal role in managing DVT, which is a condition characterized by formation of blood clots in the deep veins, especially those located in the lower extremities. The goal of this treatment is to prevent formation of blood clots and reduce recurrent thrombosis. Inhibition of the coagulation process is needed and impedes additional clots while further dissolving the existing clots. The intervention would help in alleviating symptoms linked to DVT that may include pain and swelling. At the same time, it lowers more life-threatening conditions such as pulmonary embolism.  Evidence-Based Decisions In DVT Management Research Paper

Identification of Sources of Evidence

Evidence-Based Practice (EBP) Information Cycle

The EBP information cycle is a five-step model that is characterized and categorized in five stages. The steps are ask, access, appraise, apply, and audit. In the ask stage, it involves posing a question. After a question has been asked, the next step is finding the best evidence. The third step is appraising, which involves critically appraising the validity and applicability of the evidence. The fourth step is integration of evidence with clinical expertise and preferences of the patients. Lastly, the final phase is auditing, which involves evaluating the performance and success of change in practice. The EBP information cycle is a model that would guide practitioners through the iterative process of formulation of clinical questions, searching for evidence, and critically appraising the information thus integrating it to practice (Dusin et al., 2023). Adherence to the cycle would help health professionals to ensure a systematic and ongoing approach that helps them to stay abreast of the latest evidence linked to anticoagulant therapy and management of deep vein thrombosis.

Joanna Briggs Institute (JBI) Model

Mainly, this is an evidence-based healthcare model that represents the diverse ecosystem and practical approach needed to navigate the complexities of health systems hence substantially improving health outcomes. The model is an illustration of the intersection and mechanisms of action existing between evidence-based health care. They are conceptualized and understood as context analysis, change agents, and a method that enhances evaluation of process and outcomes. The model offers a comprehensive approach to synthesis of evidence and includes systematic review, recommended practices, and summaries of available evidence hence providing health practitioners with diverse pieces of evidence that can inform decision-making in the management of DVT. The model emphasizes the critical appraisal of evidence hence ensuring that only high-quality and most relevant information is incorporated into clinical practice.  Evidence-Based Decisions In DVT Management Research Paper

AGREE II (Appraisal of Guidelines for Research and Evaluation II)

Further, AGREE II is an instrument that serves as a critical model for the evaluation of clinical practice guidelines linked to DVT management. The model allows for systematic evaluation of the methodological rigor and transparency of guidelines hence allowing health personnel to identify the most trustworthy sources that would provide evidence-based recommendations for DVT management. The model aids in the discerning of the applicability of guidelines to specific patient populations hence fostering delivery of patient-centered care.

Findings from the Articles

The article by Thaler et al. (2015) provides an overview of the current state of anticoagulant treatment for the treatment of DVT. The study highlights the evolution of treatment modalities and the emergence of oral anticoagulants. The key emphasis is to determine the efficacy of anticoagulants in treating DVT compared to traditional techniques. Further, the article by Valeriani et al. (2022) focuses on upper extremities DVT and includes systematic reviews and meta-analysis procedures to determine the efficacy and safety of anticoagulants in treating the condition. The research incorporates results from different studies that reveal that anticoagulant treatment is associated with low risk of recurrent DVT and a non-negligible risk of major bleeding. Lastly, the research by Salvi et al. (2020) provides 21 consensus statements that cover risk evaluation, prophylaxis, early diagnosis, and appropriate treatment of DVT. The findings show that anticoagulants are safe in treating DVT and eliminating life-long risks of bleeding and recurrence.  Evidence-Based Decisions In DVT Management Research Paper

Relevance of Findings

The findings underscore the importance of anticoagulants in treatment and management of DVT. The articles provided above can be used by healthcare practitioners to optimize anticoagulant therapy for DVT hence emphasizing the need to consider individual patient factors when determining the duration of treatment and address the challenges in specific patient population. Notably, these findings offer valuable insights to the risk-benefit profile of anticoagulant treatment for DVT management. Health professionals can use the information to evaluate potential outcomes of treatment strategies and thus providing a basis for informed decision-making.


Evidence-based research is crucial in informing decisions in the healthcare practice that improve patient outcomes. For this project, various EBP models have been selected as a means of guiding the answering of the PICOT question on the efficacy of anticoagulant therapy in DVT management and improvement of patient outcomes. Three articles have been selected and provided in the study whose findings are relevant to the topic and would inform evidence-based decisions in DVT management.



Dusin, J., Melanson, A., & Mische-Lawson, L. (2023). Evidence-based practice models and frameworks in the healthcare setting: A scoping review. BMJ Open, 13(5), e071188.

Salvi, A., Nitti, C., Fabbri, A., Groff, P., Ruggiero, E. G., & Agnelli, G. (2020). Diagnosis and treatment of deep vein thrombosis in the emergency department: Results of an Italian nominal group technique study. Clinical and Applied Thrombosis/Hemostasis26, 107602962095972.

Thaler, J., Pabinger, I., & Ay, C. (2015). Anticoagulant treatment of deep vein thrombosis and pulmonary embolism: The present state of the art. Frontiers in Cardiovascular Medicine2.

Valeriani, E., Di Nisio, M., Porceddu, E., Agostini, F., Pola, R., Spoto, S., Donadini, M. P., Ageno, W., & Porfidia, A. (2022). Anticoagulant treatment for upper extremity deep vein thrombosis: A systematic review and meta‐analysis. Journal of Thrombosis and Haemostasis20(3), 661-670. Evidence-Based Decisions In DVT Management Research Paper

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