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Critical Appraisal Skills Program Essay Assignment

Critical Appraisal Skills Program Essay Assignment

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Choose a research study related to your project proposal and published within the past 8 years. Critically evaluate and critique it using one of the CASP (Critical Appraisal Skills Programme) checklists included – “CASP-Cohort Study-Checklist,” “CASP-Qualitative-Checklist,” or “CASP-RCT-Checklist.”

Using the CASP checklist applicable to the type of research study you are evaluating, critically evaluate each aspect of the chosen research study, providing evidence and reasoning to support your evaluation. Identify strengths and weaknesses, discuss the implications of the findings, and suggest areas for improvement or further research. Critical Appraisal Skills Program Essay Assignment

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Notes about checklists:

FOR ALL CHECKLISTS: You must fill in the “comments” box for ALL questions (unless otherwise noted below). The comments should be in sentence format and should follow the rules of scholarly writing, good grammar, sentence structure, etc. Comments must be at least one (1) full sentence in length.

CASP-RCT Checklist:
In each question, you will select your answer AND provide a sentence explaining why you chose the answer you chose.
OMIT questions 10 and 11.

CASP Randomised Controlled Trial Standard Checklist:

11 questions to help you make sense of a randomised controlled trial (RCT)

 

Main issues for consideration: Several aspects need to be considered when appraising a randomised controlled trial: Critical Appraisal Skills Program Essay Assignment

 

Is the basic study design valid for a randomised controlled trial? (Section A)

Was the study methodologically sound? (Section B)

What are the results? (Section C)

Will the results help locally? (Section D)

 

The 11 questions in the checklist are designed to help you think about these aspects systematically.

 

How to use this appraisal tool: The first three questions (Section A) are screening questions about the validity of the basic study design and can be answered quickly. If, in light of your responses to Section A, you think the study design is valid, continue to Section B to assess whether the study was methodologically sound and if it is worth continuing with the appraisal by answering the remaining questions in Sections C and D.

 

Record ‘Yes’, ‘No’ or ‘Can’t tell’ in response to the questions. Prompts below all but one of the questions highlight the issues it is important to consider. Record the reasons for your answers in the space provided. As CASP checklists were designed to be used as educational/teaching tools in a workshop setting, we do not recommend using a scoring system. Critical Appraisal Skills Program Essay Assignment

 

 

About CASP Checklists: The CASP RCT checklist was originally based on JAMA Users’ guides to the medical literature 1994 (adapted from Guyatt GH, Sackett DL and Cook DJ), and piloted with healthcare practitioners. This version has been updated taking into account the CONSORT 2010 guideline (http://www.consort-statement.org/consort-2010, accessed 16 September 2020).

 

Citation: CASP recommends using the Harvard style, i.e., Critical Appraisal Skills Programme (2021). CASP (insert name of checklist i.e. Randomised Controlled Trial) Checklist. [online] Available at: insert URL. Accessed: insert date accessed.

 

 

©CASP this work is licensed under the Creative Commons Attribution – Non-Commercial- Share A like. To view a copy of this licence, visit https://creativecommons.org/licenses/by-sa/4.0/ Critical Appraisal Skills Program Essay Assignment

 

 

 

 

Critical Appraisal Skills Programme (CASP) www.casp-uk.net Part of OAP Ltd

 

 

Study and citation:

Treasure, M., Daly, B., Cao, S., Fu, P., Hong, A., Weinstein, E., Surdam, J., Meropol, N. J., & Dowlati, A. (2021). A randomized controlled trial of structured palliative care versus standard supportive care for patients enrolled in phase 1 clinical trials. Cancer Medicine, 10(13), 4312–4321. https://doi.org/10.1002/cam4.3971 Critical Appraisal Skills Program Essay Assignment

Section A: Is the basic study design valid for a randomised controlled trial?

 

1. Did the study address a clearly focused research question?

CONSIDER:

·           Was the study designed to assess the outcomes of an intervention?

·           Is the research question ‘focused’ in terms of:

•     Population studied

•     Intervention given

•     Comparator chosen

•     Outcomes measured?

Yes                       No                        Can’t tell

o     o      o

 

The study sought to answer the question of whether there was a significant difference between structured palliative care and usual supportive care for the symptom burden, adverse events and quality of life for cancer patients participating in phase 1 clinical trials.

The question identified the population as cancer patients, intervention as structured palliative care, comparator as usual supportive care, and outcomes measured as study duration, symptom burden, adverse events and quality of life. Critical Appraisal Skills Program Essay Assignment

2. Was the assignment of participants to interventions randomised?

CONSIDER:

•           How was randomisation carried out? Was the method appropriate?

•           Was randomisation sufficient to eliminate systematic bias?

•           Was the allocation sequence concealed from investigators and participants?

 

Yes                       No                        Can’t tell

o     o      o

 

Randomization was carried out for the intervention and comparator groups.

The method was appropriate as it ensured that all participants had the same probability of being included in any group. The allocation concealment eliminated systematic bias.

3. Were all participants who entered the study accounted for at its conclusion?

CONSIDER:

•           Were losses to follow-up and exclusions after randomisation accounted for?

•           Were participants analysed in the study groups to which they were randomised (intention-to-treat analysis)? Critical Appraisal Skills Program Essay Assignment

•           Was the study stopped early? If so, what was the reason?

 

Yes                       No                        Can’t tell

o     o      o

 

All the participants who entered the study were accounted for at its conclusion. The study was conducted to its conclusion. 85 patient participants were enrolled, and 80 patient participants completed the study. 46 caregiver participants were identified of which 46 consented to participate in the study.

 

 

Section B: Was the study methodologically sound?

 

4.  

·         Were the participants ‘blind’ to intervention they were given?

·         Were the investigators ‘blind’ to the intervention they were giving to participants?

·         Were the people assessing/analysing outcome/s ‘blinded’? Critical Appraisal Skills Program Essay Assignment

 

Yes                       No                        Can’t tell

 

o     o      o

 

 

o     o      o

 

o     o      o

5. Were the study groups similar at the start of the randomised controlled trial?

CONSIDER:

·       Were the baseline characteristics of each study group (e.g. age, sex, socio-economic group) clearly set out?

·       Were there any differences between the study groups that could affect the outcome/s?

Yes                       No                        Can’t tell

o     o      o

 

The baseline characteristics were similar, with no differences noted that could affect the outcomes. Critical Appraisal Skills Program Essay Assignment

 

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