The Severe Preeclampsia Discussion Paper
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The article was authored by Suyuthi et al. (2020). A dramatic increase in the maternal death rate in Indonesia necessitated the study. The country’s current maternal death rate is approximately 305 per 100,000 life birth, which is significantly high compared maternal death rate targeted in the Millennium Development Goals (Suyuthi et al., 2020)The Severe Preeclampsia Discussion Paper. Specifically, the high maternal death rate is associated with a substantial increase in severe preeclampsia cases in the country. The study examined the impact of oxygen saturation, creatinine, and uric acid level on maternal outcomes in expectant mothers diagnosed with severe preeclampsia. The study’s first objective was to assess the relationship between oxygen saturation and severe preeclampsia. The second objective was to examine the connection between uric acid and severe preeclampsia. The objective was to evaluate the relationship between creatinine and severe preeclampsia.
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Overview and Methodology
The authors used observational research and cross-sectional design to collect data during the study. The total sampling technique was used to select the sample population. The inclusion criteria for the study were being an expectant mother diagnosed with severe preeclampsia and hospitalized at Dr Wahidin Sudirohusodo General Hospital Makassar when the research was being conducted. Upon meeting the inclusion criteria, one hundred and thirty-five (135) participants were selected. On the other hand, the exclusion criteria included having health complications before uric acid and creatinine and oxygen saturation tests were conducted. The second exclusion criterion was a history of cardiopulmonary condition, kidney disorder, and metabolic disease. After obtaining informed consent from the participants, the researchers collected blood samples examined in the lab to check oxygen saturation, creatinine, and uric acid level The Severe Preeclampsia Discussion Paper.
Discussion and Analysis
Logistic regression analysis and Fisher’s Exact Test were used to collect data collected from the participants. The results indicated that the level of oxygen saturation (5.443) and uric acid (4.333) had significantly contributed to severe preeclampsia cases in expectant mothers (Suyuthi et al., 2020)The Severe Preeclampsia Discussion Paper. However, no correlation was reported between creatinine level and severe preeclampsia. Additionally, study findings indicated that abnormal SpO2 levels caused severe preeclampsia patients’ death. Therefore, SpO2 and uric acid levels contribute to a high mortality rate in patients with severe preeclampsia. The level of oxygen saturation and uric acid in expectant mothers should be monitored to reduce the high mortality rate among patients diagnosed with severe preeclampsia.
Clinical Trial Evaluation and Practice Application
The study’s first strength is reliable and credible evidence since data was collected through experimentation. Additionally, the findings are reliable since data were collected from a relatively large population, 135 participants. However, the study’s findings are likely biased since the randomized sampling technique did not allocate the participants to the intervention or control group. Additionally, the study was conducted from a single medical facility, limiting the generalizability of the findings. The statistical findings indicated that the level of SpO2 (5.443) and uric acid (4.333) are significant predictive factors for cases of severe preeclampsia (Suyuthi et al., 2020)The Severe Preeclampsia Discussion Paper. The authors concluded that uric acid level and oxygen saturation contribute to severe preeclampsia and high morbidity and mortality rates among pregnant women. Based on the research findings and discussion, it can be concluded that the high maternal mortality rate can be reduced by monitoring the level of oxygen saturation and uric acid during pregnancy. The study findings can be incorporated into the current clinical practice to improve oxygen saturation and uric acid level among expectant mothers, reducing maternal mortality rates. Further studies should be conducted to assess the effect of abnormal oxygen saturation and uric acid level during pregnancy on the fetus.
References
Suyuthi, F. P., Chalid, M. T., Rambulangi, S., Riu, D. S., Tiro, E., & Kasim, F. (2020). Correlation between Oxygen Saturation, Uric Acid and Creatinine Level to Maternal Outcome of a Woman with Severe Preeclampsia. Indian Journal of Forensic Medicine & Toxicology, 14(4), 7868-7872. The Severe Preeclampsia Discussion Paper
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